Concept 23 A gene is a discrete sequence of DNA nucleotides.
Links
- The Sanger Centre
- Named for Fred Sanger, the Sanger Centre is one of the centers of the Human Genome Sequencing Project. Their homepage has news and facts about the progress of various sequencing projects.
- National Center for Biotechnology Information
- An extensive site that has a lot of web resources used by research scientists to analyze sequence data. A good place to start is their Human Genome Resources, which lists news events, techniques and projects relating to the Human Genome Project.
- Genome Sequencing Center
- Located in St. Louis, the Genome Sequencing Center is one of the major sequencing centers in the United States. They have a nice overview of the overall process involved in sequencing a genome.
Bibliography
- Hargittai, I., 1999, Interview with Frederick Sanger, The Chemical Intelligencer, Springer-Verlag, New York.
- Sanger, F., and Coulson, A.R., 1975, A Rapid Method for Determining Sequences in DNA by Primed Synthesis with DNA Polymerase, Journal of Molecular Biology, 94: 441-448.
- Sanger, F., Nicklen, S., and Coulson, A.R., 1977, DNA Sequencing with Chain-terminating Inhibitors, Proc. Natl. Acad. Sci. U.S.A., 74: 5463-5467.
DNA and proteins are key molecules of the cell nucleus.
One gene makes one protein.
A gene is made of DNA.
Bacteria and viruses have DNA too.
The DNA molecule is shaped like a twisted ladder.
A half DNA ladder is a template for copying the whole.
RNA is an intermediary between DNA and protein.
DNA words are three letters long.
A gene is a discrete sequence of DNA nucleotides.
The RNA message is sometimes edited.
Some viruses store genetic information in RNA.
RNA was the first genetic molecule.
Mutations are changes in genetic information.
Some types of mutations are automatically repaired.